Dorsal Root Ganglion Block
Dorsal root ganglia (DRG), which contain the cell bodies of primary afferent neurons transmitting sensory information from the periphery to the central nervous system, play a key role in the pathogenesis of chronic pain syndromes caused by spinal pathology and peripheral nerve injury. The evidence supporting a primary role for the DRG in chronic pain states has led to the growing use of treatment directed at dorsal root ganglion.
Dorsal root ganglia are large collections of neurons on the dorsal spinal roots. Ganglia are usually located in the intervertebral foramina, immediately lateral to the perforation of the dura mater by the roots. The first and second cervical ganglia lie on the vertebral arches of the atlas and axis, respectively. The sacral ganglia lie inside the vertebral canal, and the coccygeal ganglion usually lies within the dura mater.