Botox as a Promising Treatment for Chronic Pelvic Pain in Endometriosis

October 1st, 2020
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  • Botulinum toxin (Botox) treatment can enhance the quality of life and may offer an opportunity to reduce opioid use.

What’s done here?

  • The researchers assessed the efficacy of Botox in surgically diagnosed endometriosis patients who had chronic pelvic pain despite optimal hormonal and surgical treatment and who had pelvic floor spasm on examination.

Key results:

  • Botulinum toxin injection into pelvic floor muscles significantly reduced both palpable muscle spasm and self-reported pain as well as the use of other pain medications. It also probably relief the pain by direct effects on nociception.
  • The response to Botox was often prolonged (more than 6 months of relief). The benefit of Botox can be sustained by repeated injections.
  • After Botox injection, the patients did not report any urinary retention or incontinence.
  • Botox treatment may make patients more responsive to other pain relief modalities such as pelvic floor physical therapy which is usually not well-tolerated since it causes extreme pain.
  • Since Botox don’t have many drug interactions, it can be used in combination with oral medications, hormones, and surgery.
  • Botox treats pelvic pain by reducing muscle spasm and probably has direct effects on nociception.

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At Pain Spa, Dr. Krishna is highly experienced in performing injections under ultrasound guidance. Please contact us for further details if you are interested in this treatment option.